What is CINV?

CINV stands for chemotherapy-induced nausea and vomiting. Chemotherapy is a type of cancer treatment. Many people feel nauseous or vomit when they get chemotherapy. In fact, about three-quarters of those receiving chemotherapy have CINV.1 This can happen while treatment is being given in the hospital or clinic, or later, when patients are at home.

What are nausea and vomiting?

Nausea and vomiting are 2 related symptoms that may occur at the same time. Vomiting is "throwing up" the contents of your stomach. Before a person vomits, (s)he usually feels nauseous.

Nausea is a feeling of queasiness or sickness in your stomach and sometimes in your throat. It can also make you dizzy or lightheaded, have increased saliva (spit), trouble swallowing, skin temperature changes, or a fast heart rate. Even though nausea makes you feel like you’re going to throw up, it can occur without vomiting.2

To learn more about CINV, click on the links below.

Please see Full Prescribing Information and see below for important risk information.

Next: How CINV Occurs

References:

  1. Berger AM, Clark-Snow RA. Adverse effects of treatment. In: DeVita VJ Jr et al. Cancer: Principles and Practice of Oncology. 6th ed. Philadelphia: Lippincott, Williams and Wilkins; 2001:2869-2880.
  2. American Cancer Society. What is nausea and vomiting? Available at: www.cancer.org/docroot/MBC/content/MBC_2X_Nausea_and_Vomiting.asp?sitearea=MBC. Accessed June 9, 2010.

Cesamet Indication

  • Cesamet is a medicine for nausea and vomiting caused by cancer chemotherapy. It is used when other drugs have not been able to control these symptoms. The scientific name of Cesamet is nabilone.
  • Doctors prescribe other drugs first because Cesamet can affect your mental state. Other nausea and vomiting drugs usually do not have this kind of side effect.
  • Cesamet can affect your mental state, so you should take it around an adult you trust. This is most important when you first take Cesamet and if your doctor changes your dose.
  • Cesamet can be abused, so there are laws about how doctors can prescribe it. Prescriptions for Cesamet should last for just a few days.
  • Your doctor might watch you for signs of abusing Cesamet. If you or a family member has ever abused drugs or had a mental illness, you might have a higher risk of abusing Cesamet.
  • Only take Cesamet when your doctor told you to. It should not be the first drug you take for nausea and vomiting.

Cesamet Important Risk Information

  • Do not take Cesamet if you are allergic to any of its ingredients or any other cannabinoids.
  • The effects of Cesamet last longer in some people than others. Mental side effects could last for 2 or 3 days after you stop taking it.
  • Cesamet works in your brain. You might feel dizzy, sleepy, "high", uncoordinated, anxious, confused, or depressed while taking Cesamet. You might also hear or see things that are not real.
  • Cesamet can make your heart race or blood pressure drop. Ask your doctor about this if you are older or have high blood pressure or heart disease.
  • Cesamet affects people differently. You should take Cesamet around an adult you trust. This is most important when you first take Cesamet or if your doctor changes your dose.
  • Do not drive, use machines, or do other activities that could be dangerous until you know how Cesamet affects you.
  • Do not drink alcohol, take sleeping pills, or take other medicines that affect your brain while you are taking Cesamet. If you do, the side effects of Cesamet could be worse.
  • Talk to your doctor if you have ever had depression, schizophrenia, bipolar disorder, or another mental disorder. Cesamet could bring out the symptoms of these illnesses.
  • Cesamet is similar to marijuana. Tell your doctor if you ever abused or were dependent on alcohol or marijuana.
  • Cesamet has not been studied in pregnant women, nursing mothers, or children. These patients should be careful when taking Cesamet.
  • Cesamet can change heart rhythms. The effects of these changes in heart rhythms are not known.
  • In scientific studies, most patients who took Cesamet had at least one side effect. The most common side effects were sleepiness, dizziness, dry mouth, a "high" feeling, an uncoordinated feeling, a headache, and problems concentrating.

Cesamet Important Risk Information

  • Do not take Cesamet if you are allergic to any of its ingredients or any other cannabinoids.
  • The effects of Cesamet last longer in some people than others. Mental side effects could last for 2 or 3 days after you stop taking it.
  • Cesamet works in your brain. You might feel dizzy, sleepy, "high", uncoordinated, anxious, confused, or depressed while taking Cesamet. You might also hear or see things that are not real.
  • Cesamet can make your heart race or blood pressure drop. Ask your doctor about this if you are older or have high blood pressure or heart disease.
  • Cesamet affects people differently. You should take Cesamet around an adult you trust. This is most important when you first take Cesamet or if your doctor changes your dose.
  • Do not drive, use machines, or do other activities that could be dangerous until you know how Cesamet affects you.
  • Do not drink alcohol, take sleeping pills, or take other medicines that affect your brain while you are taking Cesamet. If you do, the side effects of Cesamet could be worse.
  • Talk to your doctor if you have ever had depression, schizophrenia, bipolar disorder, or another mental disorder. Cesamet could bring out the symptoms of these illnesses.
  • Cesamet is similar to marijuana. Tell your doctor if you ever abused or were dependent on alcohol or marijuana.
  • Cesamet has not been studied in pregnant women, nursing mothers, or children. These patients should be careful when taking Cesamet.
  • Cesamet can change heart rhythms. The effects of these changes in heart rhythms are not known.
  • In scientific studies, most patients who took Cesamet had at least one side effect. The most common side effects were sleepiness, dizziness, dry mouth, a "high" feeling, an uncoordinated feeling, a headache, and problems concentrating.

Cesamet Indication

  • Cesamet is a medicine for nausea and vomiting caused by cancer chemotherapy. It is used when other drugs have not been able to control these symptoms. The scientific name of Cesamet is nabilone.
  • Doctors prescribe other drugs first because Cesamet can affect your mental state. Other nausea and vomiting drugs usually do not have this kind of side effect.
  • Cesamet can affect your mental state, so you should take it around an adult you trust. This is most important when you first take Cesamet and if your doctor changes your dose.
  • Cesamet can be abused, so there are laws about how doctors can prescribe it. Prescriptions for Cesamet should last for just a few days.
  • Your doctor might watch you for signs of abusing Cesamet. If you or a family member has ever abused drugs or had a mental illness, you might have a higher risk of abusing Cesamet.
  • Only take Cesamet when your doctor told you to. It should not be the first drug you take for nausea and vomiting.